Nikej Shah, MD

Chief Executive Officer

Dr. Shah is Founder, CEO, interim Chief Medical Officer and Co-Inventor of Nirsum’s foundational intellectual property. He is also Co-Principal Investigator on our Cooperative Agreement with the National Institutes of Health/ National Institute On Drug Abuse. He brings over 20 years of experience in various roles as a physician-scientist, entrepreneur, and investor. Dr. Shah is also the Founder and Managing Partner of biotech-focused investment firm Mountain Brook Capital, the Founding Investor in Nirsum. He was previously a Senior Healthcare Portfolio Manager at Sigma Capital Management (now Point 72), and at HBK Capital Management. He was also a Managing Director at healthcare public/ private equity investor Great Point Partners and Analyst at Ursus Capital. Dr. Shah earned an MD at the New York University School of Medicine and BS at Cornell University. He was a practicing emergency physician, having completed residency at the New York University/Bellevue Hospital Center, where he gained extensive experience with the acute treatment and referral of patients with opioid use disorder (OUD).

Dan Deaver, PhD

Chief Scientific Officer

Dr. Deaver is Chief Scientific Officer of Nirsum. His professional career spans over 35 years and includes extensive experience in academia and the biopharmaceutical industry. He is also Principal of Deaver Nonclinical Drug Development Consulting, LLC. He retired from Alkermes as Vice-President of Nonclinical R&D in 2016 after 17 years with the company. At Alkermes he provided leadership and scientific oversight for all biological aspects of nonclinical R&D. He was actively involved in the oversight of medicinal chemistry, pharmacology and toxicology efforts directed towards expanding Alkermes internal drug portfolio. He was directly involved with three programs that lead to marketed drugs – Vivitrol®, Bydureon® and Aristada®. Prior to Alkermes, Dr. Deaver was Professor, of Reproductive Physiology at Penn State University, and Chair of the Intercollege Graduate Program in Physiology. He has been awarded numerous U.S. patents, and has published extensively with over 125 papers, book chapters and abstracts. Dr. Deaver received his BS and MS degrees from University of Maryland College Park, and his PhD degree from West Virginia University.

Mark Sorenson, PhD

Chief Development Officer

Dr Sorenson is Chief Development Officer of Nirsum. He brings over 25 years of experience in the pharmaceutical industry to Nirsum. Dr. Sorenson has extensive experience consulting for pharmaceutical companies where he provides Chemistry, Manufacturing and Controls (CMC) leadership associated with the development of small molecule new chemical entities. His areas of expertise include analytical method development/validation and transfers, stability programs and data assessment, chemical process development, formulation and process development, API and drug product manufacturing and CMC regulatory document preparation. He previously held positions of increasing responsibility at Agouron Pharmaceuticals, Pfizer, and MGI Pharma. Dr. Sorenson earned his PhD in Pharmaceutics and BS in Pharmacy at the University of Minnesota.